B cell depletion reduces the number of autoreactive T helper cells and prevents glucose-6-phosphate isomerase-induced arthritis.
The therapeutic benefit of B cell depletion in patients with rheumatoid arthritis has provided proof of concept that B cells are relevant ALMOND SOAP for the pathogenesis of arthritis.It remains unknown which B cell effector functions contribute to the induction or chronification of arthritis.We studied the clinical and immunological effects of B c